Research Design Types
Randomized, Controlled Trials - This is a prospective, analytical, experimental study using primary data generated in the clinical environment. Subjects are randomly allocated to two or more groups (treatment and control). The outcomes of the groups are compared at the conclusion of the study.
Case Reports - Reports on the treatment of a single patient. A Case Series reports on the treatment of multiple individual patients.
Cohort Study - Identifies a group of patients who are already taking a particular treatment or have an exposure, follows them forward over time, and then compares their outcomes with a similar group not affected by the treatment or exposure.
Prospective, Blind Comparison to a Gold Standard Study - A study that shows the efficacy of a diagnostic test. This is a controlled trial that studies patients with varying degrees of an illness and administers both diagnostic tests--the test under investigation and the "gold standard" test.
Literature Reviews - Includes narrative reviews, meta-analyses, systematic reviews, and other evidence synthesis projects.
Other - There are additional study types to the ones listed here, including Position Statements, Guidelines, Critically Appraised Topics, and others. You can find these studies in peer reviewed journals, and/or on the websites of the organization that published the statement.
Ghezzi-Kopel, Kate. (2019, September 16). Developing your research question. (research guide). Retrieved from https://guides.library.cornell.edu/systematic_reviews/research_question
Exercise Physiology is a complex discipline, with many intersecting considerations. At this stage in the process, consider what interests you most or where you would like to learn more when brainstorming topics. You are aiming to ask a specific question, such as
OR assess an intervention
OR synthesize the existing evidence
Whatever your aim, formulating a clear, well-defined research question of appropriate scope is key to success. The research question will be the foundation of your research project.
Formulating a research question takes time and your team may go through different versions until settling on the right research question. A research question framework can help structure your systematic review question.
PICO/T is an acronym which stands for
Each PICO includes at least a P, I, and an O, and some include a C or a T. Below are some sample PICO/T questions to help you use the framework to your advantage.
For an intervention/therapy
In _______(P), what is the effect of _______(I) on ______(O) compared with
_______(C) within ________ (T)?
For etiology
Are ____ (P) who have _______ (I) at ___ (Increased/decreased) risk for/of_______ (O) compared with ______ (P) with/without ______ (C) over _____ (T)?
Diagnosis or diagnostic test
Are (is) _________ (I) more accurate in diagnosing ________ (P) compared with ______ (C) for _______ (O)?
Prevention
For ________ (P) does the use of ______ (I) reduce the future risk of ________ (O) compared with _________ (C)?
Prognosis/Predictions
Does __________ (I) influence ________ (O) in patients who have _______ (P) over ______ (T)?
Meaning
How do ________ (P) diagnosed with _______ (I) perceive ______ (O) during _____ (T)?